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Recurrent rearrangements of FOS and FOSB define osteoblastoma
The transcription factor FOS has long been implicated in the pathogenesis of bone tumours, following the discovery that the viral homologue, v-fos, caused osteosarcoma in laboratory mice. However, mutations of FOS have not been found in human bone-forming tumours. Here, we report recurrent rearrange...
Autores principales: | Fittall, Matthew W., Mifsud, William, Pillay, Nischalan, Ye, Hongtao, Strobl, Anna-Christina, Verfaillie, Annelien, Demeulemeester, Jonas, Zhang, Lei, Berisha, Fitim, Tarabichi, Maxime, Young, Matthew D., Miranda, Elena, Tarpey, Patrick S., Tirabosco, Roberto, Amary, Fernanda, Grigoriadis, Agamemnon E., Stratton, Michael R., Van Loo, Peter, Antonescu, Cristina R., Campbell, Peter J., Flanagan, Adrienne M., Behjati, Sam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984627/ https://www.ncbi.nlm.nih.gov/pubmed/29858576 http://dx.doi.org/10.1038/s41467-018-04530-z |
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