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Cellular conditions of weakly chelated magnesium ions strongly promote RNA stability and catalysis
Most RNA folding studies have been performed under non-physiological conditions of high concentrations (≥10 mM) of Mg(2+)(free), while actual cellular concentrations of Mg(2+)(free) are only ~1 mM in a background of greater than 50 mM Mg(2+)(total). To uncover cellular behavior of RNA, we devised cy...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984629/ https://www.ncbi.nlm.nih.gov/pubmed/29858572 http://dx.doi.org/10.1038/s41467-018-04415-1 |