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YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling

YAP (yes-associated protein) is a transcriptional factor that is negatively regulated by Hippo pathway, a conserved pathway for the development and size control of multiple organs. The exact function of YAP in bone homeostasis remains controversial. Here we provide evidence for YAP’s function in pro...

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Detalles Bibliográficos
Autores principales: Pan, Jin-Xiu, Xiong, Lei, Zhao, Kai, Zeng, Peng, Wang, Bo, Tang, Fu-Lei, Sun, Dong, Guo, Hao-han, Yang, Xiao, Cui, Shun, Xia, Wen-Fang, Mei, Lin, Xiong, Wen-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984632/
https://www.ncbi.nlm.nih.gov/pubmed/29872550
http://dx.doi.org/10.1038/s41413-018-0018-7