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O-GlcNAc cycling in the developing, adult and geriatric brain

Hundreds of proteins in the nervous system are modified by the monosaccharide O-GlcNAc. A single protein is often O-GlcNAcylated on several amino acids and the modification of a single site can play a crucial role for the function of the protein. Despite its complexity, only two enzymes add and remo...

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Detalles Bibliográficos
Autor principal: Lagerlöf, Olof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984647/
https://www.ncbi.nlm.nih.gov/pubmed/29790000
http://dx.doi.org/10.1007/s10863-018-9760-1