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Silencing Formin-like 2 inhibits growth and metastasis of gastric cancer cells through suppressing internalization of integrins

BACKGROUND: Formin-like 2 (FMNL2) is a member of Formin family which governs cytokinesis, cellular polarity and morphogenesis. Dysregulation of FMNL2 has been discovered in cancers and is closely related to cancers. However, the role of FMNL2 in gastric cancer remains unclear. In this study, we aime...

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Detalles Bibliográficos
Autores principales: Zhong, Banghua, Wang, Kewei, Xu, Hao, Kong, Fanmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984784/
https://www.ncbi.nlm.nih.gov/pubmed/29881327
http://dx.doi.org/10.1186/s12935-018-0576-1