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Strong correlation of downregulated genes related to synaptic transmission and mitochondria in post-mortem autism cerebral cortex

BACKGROUND: Genetic studies in autism have pinpointed a heterogeneous group of loci and genes. Further, environment may be an additional factor conferring susceptibility to autism. Transcriptome studies investigate quantitative differences in gene expression between patient-derived tissues and contr...

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Detalles Bibliográficos
Autores principales: Schwede, Matthew, Nagpal, Shailender, Gandal, Michael J., Parikshak, Neelroop N., Mirnics, Karoly, Geschwind, Daniel H., Morrow, Eric M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984825/
https://www.ncbi.nlm.nih.gov/pubmed/29859039
http://dx.doi.org/10.1186/s11689-018-9237-x