Dissecting the Forces that Dominate Dimerization of the Nucleotide Binding Domains of ABCB1

P-glycoprotein, also known as multidrug resistance protein 1 or ABCB1, can export a wide range of chemically unrelated compounds, including chemotherapeutic drugs. ABCB1 consists of two transmembrane domains that form the substrate binding and translocation domain, and of two cytoplasmic nucleotide...

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Detalles Bibliográficos
Autores principales: Szöllősi, Dániel, Szakács, Gergely, Chiba, Peter, Stockner, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2018
Materias:
Channels and Transporters
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984967/
https://www.ncbi.nlm.nih.gov/pubmed/29401431
http://dx.doi.org/10.1016/j.bpj.2017.11.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984967/
https://www.ncbi.nlm.nih.gov/pubmed/29401431
http://dx.doi.org/10.1016/j.bpj.2017.11.022

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