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Dissecting the Forces that Dominate Dimerization of the Nucleotide Binding Domains of ABCB1
P-glycoprotein, also known as multidrug resistance protein 1 or ABCB1, can export a wide range of chemically unrelated compounds, including chemotherapeutic drugs. ABCB1 consists of two transmembrane domains that form the substrate binding and translocation domain, and of two cytoplasmic nucleotide...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Biophysical Society
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5984967/ https://www.ncbi.nlm.nih.gov/pubmed/29401431 http://dx.doi.org/10.1016/j.bpj.2017.11.022 |