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Cdkn2a deficiency promotes adipose tissue browning

OBJECTIVES: Genome-wide association studies have reported that DNA polymorphisms at the CDKN2A locus modulate fasting glucose in human and contribute to type 2 diabetes (T2D) risk. Yet the causal relationship between this gene and defective energy homeostasis remains elusive. Here we sought to under...

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Detalles Bibliográficos
Autores principales: Rabhi, Nabil, Hannou, Sarah Anissa, Gromada, Xavier, Salas, Elisabet, Yao, Xi, Oger, Frédérik, Carney, Charlène, Lopez-Mejia, Isabel C., Durand, Emmanuelle, Rabearivelo, Iandry, Bonnefond, Amélie, Caron, Emilie, Fajas, Lluis, Dani, Christian, Froguel, Philippe, Annicotte, Jean-Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985036/
https://www.ncbi.nlm.nih.gov/pubmed/29237539
http://dx.doi.org/10.1016/j.molmet.2017.11.012