Cargando…

Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding

OBJECTIVE: Hepatocyte deletion of estrogen receptor alpha (LKO-ERα) worsens fatty liver, dyslipidemia, and insulin resistance in high-fat diet fed female mice. However, whether or not hepatocyte ERα regulates reverse cholesterol transport (RCT) in mice has not yet been reported. METHODS AND RESULTS:...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhu, Lin, Shi, Jeanne, Luu, Thao N., Neuman, Joshua C., Trefts, Elijah, Yu, Sophia, Palmisano, Brian T., Wasserman, David H., Linton, MacRae F., Stafford, John M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985047/
https://www.ncbi.nlm.nih.gov/pubmed/29331506
http://dx.doi.org/10.1016/j.molmet.2017.12.012