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Hepatocyte estrogen receptor alpha mediates estrogen action to promote reverse cholesterol transport during Western-type diet feeding
OBJECTIVE: Hepatocyte deletion of estrogen receptor alpha (LKO-ERα) worsens fatty liver, dyslipidemia, and insulin resistance in high-fat diet fed female mice. However, whether or not hepatocyte ERα regulates reverse cholesterol transport (RCT) in mice has not yet been reported. METHODS AND RESULTS:...
Autores principales: | Zhu, Lin, Shi, Jeanne, Luu, Thao N., Neuman, Joshua C., Trefts, Elijah, Yu, Sophia, Palmisano, Brian T., Wasserman, David H., Linton, MacRae F., Stafford, John M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985047/ https://www.ncbi.nlm.nih.gov/pubmed/29331506 http://dx.doi.org/10.1016/j.molmet.2017.12.012 |
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