The RhoGAP Stard13 controls insulin secretion through F-actin remodeling

OBJECTIVE: Actin cytoskeleton remodeling is necessary for glucose-stimulated insulin secretion in pancreatic β-cells. A mechanistic understanding of actin dynamics in the islet is paramount to a better comprehension of β-cell dysfunction in diabetes. Here, we investigate the Rho GTPase regulator Sta...

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Detalles Bibliográficos
Autores principales: Naumann, Heike, Rathjen, Thomas, Poy, Matthew N., Spagnoli, Francesca M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985048/
https://www.ncbi.nlm.nih.gov/pubmed/29310936
http://dx.doi.org/10.1016/j.molmet.2017.12.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985048/
https://www.ncbi.nlm.nih.gov/pubmed/29310936
http://dx.doi.org/10.1016/j.molmet.2017.12.013

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