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Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease

OBJECTIVE: The very low-density lipoprotein receptor (VLDLR) plays an important role in the development of hepatic steatosis. In this study, we investigated the role of Peroxisome Proliferator-Activated Receptor (PPAR)β/δ and fibroblast growth factor 21 (FGF21) in hepatic VLDLR regulation. METHODS:...

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Detalles Bibliográficos
Autores principales: Zarei, Mohammad, Barroso, Emma, Palomer, Xavier, Dai, Jianli, Rada, Patricia, Quesada-López, Tania, Escolà-Gil, Joan Carles, Cedó, Lidia, Zali, Mohammad Reza, Molaei, Mahsa, Dabiri, Reza, Vázquez, Santiago, Pujol, Eugènia, Valverde, Ángela M., Villarroya, Francesc, Liu, Yong, Wahli, Walter, Vázquez-Carrera, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985050/
https://www.ncbi.nlm.nih.gov/pubmed/29289645
http://dx.doi.org/10.1016/j.molmet.2017.12.008