Cargando…

Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease

OBJECTIVE: The very low-density lipoprotein receptor (VLDLR) plays an important role in the development of hepatic steatosis. In this study, we investigated the role of Peroxisome Proliferator-Activated Receptor (PPAR)β/δ and fibroblast growth factor 21 (FGF21) in hepatic VLDLR regulation. METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zarei, Mohammad, Barroso, Emma, Palomer, Xavier, Dai, Jianli, Rada, Patricia, Quesada-López, Tania, Escolà-Gil, Joan Carles, Cedó, Lidia, Zali, Mohammad Reza, Molaei, Mahsa, Dabiri, Reza, Vázquez, Santiago, Pujol, Eugènia, Valverde, Ángela M., Villarroya, Francesc, Liu, Yong, Wahli, Walter, Vázquez-Carrera, Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985050/ https://www.ncbi.nlm.nih.gov/pubmed/29289645 http://dx.doi.org/10.1016/j.molmet.2017.12.008

Ejemplares similares

SIRT3 deficiency exacerbates fatty liver by attenuating the HIF1α-LIPIN 1 pathway and increasing CD36 through Nrf2
por: Barroso, Emma, et al.
Publicado: (2020)

The PPARβ/δ-AMPK Connection in the Treatment of Insulin Resistance
por: Aguilar-Recarte, David, et al.
Publicado: (2021)

PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders
por: Palomer, Xavier, et al.
Publicado: (2018)

The prevalence of Helicobacter pylori is decreasing in Iranian patients
por: Ashtari, Sara, et al.
Publicado: (2015)

Endoplasmic reticulum stress downregulates PGC-1α in skeletal muscle through ATF4 and an mTOR-mediated reduction of CRTC2
por: Montori-Grau, Marta, et al.
Publicado: (2022)

Mucins in neoplastic spectrum of colorectal polyps: can they provide predictions?
por: Molaei, Mahsa, et al.
Publicado: (2010)

Duodenal adenocarcinoma might be the cause of intractable nausea and vomiting in patient with coeliac disease
por: Rajabalinia, Hassan, et al.
Publicado: (2012)

Activation of Peroxisome Proliferator–Activated Receptor-β/-δ (PPAR-β/-δ) Ameliorates Insulin Signaling and Reduces SOCS3 Levels by Inhibiting STAT3 in Interleukin-6–Stimulated Adipocytes
por: Serrano-Marco, Lucía, et al.
Publicado: (2011)

A Patient with Chronic Hepatitis C and a Pancreatic Mass in Endoscopic Ultrasound
por: Ghobakhlou, Mehdi, et al.
Publicado: (2012)

Alanine to Serine Variant at Position 986 of Calcium Sensing Receptor and Colorectal Cancer Risk
por: Dabiri, Reza, et al.
Publicado: (2016)

Genetic Variations in Leptin and Leptin Receptor and Susceptibility to Colorectal Cancer and Obesity
por: Mahmoudi, Touraj, et al.
Publicado: (2016)

Design and Synthesis of AMPK Activators and GDF15 Inducers
por: Zhang, Meijian, et al.
Publicado: (2023)

An experimental model of colitis induced by dextran sulfate sodium from acute progresses to chronicity in C57BL/6: correlation between conditions of mice and the environment
por: Taghipour, Niloofar, et al.
Publicado: (2016)

PPARs as Key Mediators in the Regulation of Metabolism and Inflammation
por: Vázquez-Carrera, Manuel, et al.
Publicado: (2022)

VLDL-associated mutagenic activity.
por: Gomes, M. I., et al.
Publicado: (1982)

HDL and LDL: Potential New Players in Breast Cancer Development
por: Cedó, Lídia, et al.
Publicado: (2019)

Bariatric surgery improves postprandial VLDL kinetics and restores insulin-mediated regulation of hepatic VLDL production
por: Yildirim, Vehpi, et al.
Publicado: (2023)

Lack of BRAFV600E mutation in stage I and II of colorectal cancer
por: Molaei, Mahsa, et al.
Publicado: (2016)

FGF21 and Cardiac Physiopathology
por: Planavila, Anna, et al.
Publicado: (2015)

The Effectiveness of Neurofeedback on Enhancing Cognitive Process Involved in Entrepreneurship Abilities among Primary School Students in District No. 3 Tehran
por: Rahmati, Narges, et al.
Publicado: (2014)

Triglyceride Rich Lipoprotein -LPL-VLDL Receptor and Lp(a)-VLDL Receptor Pathways for Macrophage Foam Cell Formation
por: Takahashi, Sadao
Publicado: (2017)

Gut microbiota, epigenetic modification and colorectal cancer
por: Rezasoltani, Sama, et al.
Publicado: (2017)

Trimethylamine N-Oxide: A Link among Diet, Gut Microbiota, Gene Regulation of Liver and Intestine Cholesterol Homeostasis and HDL Function
por: Canyelles, Marina, et al.
Publicado: (2018)

The Role of Peroxisome Proliferator-Activated Receptor β/δ on the Inflammatory Basis of Metabolic Disease
por: Coll, Teresa, et al.
Publicado: (2010)

Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue
por: Villarroya, Joan, et al.
Publicado: (2018)

Activation of Peroxisome Proliferator–Activated Receptor β/δ Inhibits Lipopolysaccharide-Induced Cytokine Production in Adipocytes by Lowering Nuclear Factor-κB Activity via Extracellular Signal–Related Kinase 1/2
por: Rodríguez-Calvo, Ricardo, et al.
Publicado: (2008)

Association of adiponectin receptor 1 gene − 106 C > T variant with susceptibility to colorectal cancer
por: Mahmoudi, Touraj, et al.
Publicado: (2016)

Effects of Electronegative VLDL on Endothelium Damage in Metabolic Syndrome
por: Chen, Chu-Huang, et al.
Publicado: (2012)

VLDL receptor gene therapy for reducing atherogenic lipoproteins
por: Krauss, Ronald M., et al.
Publicado: (2023)

Prognostic Significance of Nuclear β-Catenin Expression in Patients with Colorectal Cancer from Iran
por: Nazemalhosseini Mojarad, Ehsan, et al.
Publicado: (2015)

Identification and Characterization of a High Vancomycin-Resistant Staphylococcus aureus Harboring VanA Gene Cluster Isolated from Diabetic Foot Ulcer
por: Dezfulian, Anahita, et al.
Publicado: (2012)

Decreases in the Serum VLDL-TG/Non-VLDL-TG Ratio from Early Stages of Chronic Hepatitis C: Alterations in TG-Rich Lipoprotein Levels
por: Nishimura, Motoi, et al.
Publicado: (2011)

Comparative assessment of LDL-C and VLDL-C estimation in familial combined hyperlipidemia using Sampson’s, Martin’s and Friedewald’s equations
por: Vargas-Vázquez, Arsenio, et al.
Publicado: (2021)

Combined LDL and VLDL Electronegativity Correlates with Coronary Heart Disease Risk in Asymptomatic Individuals
por: Shen, Ming-Yi, et al.
Publicado: (2019)

Adiponectin Reduces Plasma Triglyceride by Increasing VLDL Triglyceride Catabolism
por: Qiao, Liping, et al.
Publicado: (2008)

Mathematical modelling of competitive LDL/VLDL binding and uptake by hepatocytes
por: Pearson, T., et al.
Publicado: (2008)

Progesterone Regulation of Milk Fat Globule Size Is VLDL Dependent
por: Argov-Argaman, Nurit, et al.
Publicado: (2020)

SIRT3-mediated inhibition of FOS through histone H3 deacetylation prevents cardiac fibrosis and inflammation
por: Palomer, Xavier, et al.
Publicado: (2020)

Facing resistance of H.pylori infection
por: Zali, Mohammad Reza
Publicado: (2011)

The role of FGF21 and its analogs on liver associated diseases
por: Falamarzi, Kimia, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rba6i1lal9usfaffh9mtrc4gld