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Toll-like receptor 2 activation primes and upregulates osteoclastogenesis via lox-1

BACKGROUND: Lectin-like oxidized low-density-lipoprotein receptor 1 (Lox-1) is the receptor for oxidized low-density lipoprotein (oxLDL), a mediator in dyslipidemia. Toll-like receptor (TLR)-2 and − 4 are receptors of lipopolysaccharide (LPS) from Porphyromonas gingivalis, a major pathogen of chroni...

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Detalles Bibliográficos
Autores principales: Ohgi, Kimiko, Kajiya, Hiroshi, Goto-T, Kazuko, Okamoto, Fujio, Yoshinaga, Yasunori, Okabe, Koji, Sakagami, Ryuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985062/
https://www.ncbi.nlm.nih.gov/pubmed/29859535
http://dx.doi.org/10.1186/s12944-018-0787-4