LC-MS/MS Method for Simultaneous Quantification of Dexmedetomidine, Dezocine, and Midazolam in Rat Plasma and Its Application to Their Pharmacokinetic Study

A simple, sensitive, and accurate LC-MS/MS method was established and validated for the simultaneous quantification of dexmedetomidine, dezocine, and midazolam in rat plasma. Chromatographic separation was achieved on a C18 column (50 mm × 2.1 mm, 3 µm) using a mobile phase composed of water (contai...

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Detalles Bibliográficos
Autores principales: Cui, Wenjuan, Liu, Qin, Xiong, Shan, Qiao, Lujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985101/
https://www.ncbi.nlm.nih.gov/pubmed/29888025
http://dx.doi.org/10.1155/2018/3184759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985101/
https://www.ncbi.nlm.nih.gov/pubmed/29888025
http://dx.doi.org/10.1155/2018/3184759

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