Loratadine-Loaded Thermoresponsive Hydrogel: Characterization and Ex-vivo Rabbit Cornea Permeability Studies

Poor bioavailability of ophthalmic drops is mainly due to drainage through the nasal-lacrimal duct and a very low permeability through corneal epithelium. The aim of our study was to prepare and characterize an ocular hydrogel of loratadine, as an example of a lipophilic drug, to increase drug conce...

Descripción completa

Detalles Bibliográficos
Autores principales: Sharif Makhmalzadeh, Behzad, Salimi, Anayatollah, Niroomand, Aida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985164/
https://www.ncbi.nlm.nih.gov/pubmed/29881404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985164/
https://www.ncbi.nlm.nih.gov/pubmed/29881404

Ejemplares similares