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Isolation and Characterization of Novel Phage Displayed scFv Fragment for Human Tumor Necrosis Factor Alpha and Molecular Docking Analysis of Their Interactions

Tumor necrosis factor alpha (TNF-α) expression amplifies to excess amounts in several disorders such as rheumatoid arthritis and psoriasis. Although, Anti-TNF biologics have revolutionized the treatment of these autoimmune diseases, formation of anti-drug antibodies (ADA) has dramatically affected t...

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Detalles Bibliográficos
Autores principales: Safarpour, Hossein, Shahmirzaie, Morteza, Rezaee, Elham, Barati, Mahmood, Safarnejad, Mohammad Reza, H. Shirazi, Farshad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985191/
https://www.ncbi.nlm.nih.gov/pubmed/29881431