Degradation of brown adipocyte purine nucleotides regulates uncoupling protein 1 activity

OBJECTIVE: Non-shivering thermogenesis in mammalian brown adipose tissue depends on thermogenic uncoupling protein 1. Its activity is triggered by free fatty acids while purine nucleotides mediate inhibition. During activation, it is thought that free fatty acids overcome purine-mediated inhibition....

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Detalles Bibliográficos
Autores principales: Fromme, Tobias, Kleigrewe, Karin, Dunkel, Andreas, Retzler, Angelika, Li, Yongguo, Maurer, Stefanie, Fischer, Natascha, Diezko, Rolf, Kanzleiter, Timo, Hirschberg, Verena, Hofmann, Thomas, Klingenspor, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985227/
https://www.ncbi.nlm.nih.gov/pubmed/29310935
http://dx.doi.org/10.1016/j.molmet.2017.12.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985227/
https://www.ncbi.nlm.nih.gov/pubmed/29310935
http://dx.doi.org/10.1016/j.molmet.2017.12.010

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