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Nucleus accumbens inflammation mediates anxiodepressive behavior and compulsive sucrose seeking elicited by saturated dietary fat

OBJECTIVE: The incidence of depression is significantly compounded by obesity. Obesity arising from excessive intake of high-fat food provokes anxiodepressive behavior and elicits molecular adaptations in the nucleus accumbens (NAc), a region well-implicated in the hedonic deficits associated with d...

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Detalles Bibliográficos
Autores principales: Décarie-Spain, Léa, Sharma, Sandeep, Hryhorczuk, Cécile, Issa-Garcia, Victor, Barker, Philip A., Arbour, Nathalie, Alquier, Thierry, Fulton, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985233/
https://www.ncbi.nlm.nih.gov/pubmed/29454579
http://dx.doi.org/10.1016/j.molmet.2018.01.018