Activation of Sirtuin 1 Attenuates High Glucose-Induced Neuronal Apoptosis by Deacetylating p53

Diabetes mellitus (DM) has been proven to be a key risk factor for cognitive impairment. Previous studies have implicated hippocampal neuronal apoptosis in diabetes-related cognitive impairment. However, the underlying mechanism remains unknown. Sirtuin 1 (SIRT1) is a protein deacetylase depended on...

Descripción completa

Detalles Bibliográficos
Autores principales: Shi, Xiajie, Pi, Linhua, Zhou, Shanlei, Li, Xin, Min, Fangyuan, Wang, Shan, Liu, Zhenqi, Wu, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985296/
https://www.ncbi.nlm.nih.gov/pubmed/29892266
http://dx.doi.org/10.3389/fendo.2018.00274

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985296/
https://www.ncbi.nlm.nih.gov/pubmed/29892266
http://dx.doi.org/10.3389/fendo.2018.00274

Ejemplares similares