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IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells

Natural killer (NK) cells are innate lymphocytes that play essential roles in mediating antitumor immunity. NK cells respond to various inflammatory stimuli including cytokines and stress-induced cellular ligands which activate germline-encoded activation receptors (NKRs), such as NKG2D. The signali...

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Detalles Bibliográficos
Autores principales: Abel, Alex M., Tiwari, Aradhana A., Gerbec, Zachary J., Siebert, Jason R., Yang, Chao, Schloemer, Nathan J., Dixon, Kate J., Thakar, Monica S., Malarkannan, Subramaniam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985319/
https://www.ncbi.nlm.nih.gov/pubmed/29892299
http://dx.doi.org/10.3389/fimmu.2018.01168