Cargando…

Melatonin Attenuates Dysregulation of the Circadian Clock Pathway in Mice With CCl(4)-Induced Fibrosis and Human Hepatic Stellate Cells

Dysregulation of the circadian clock machinery is a critical mechanism in the pathogenesis of fibrosis. This study aimed to investigate whether the antifibrotic effect of melatonin is associated with attenuation of circadian clock pathway disturbances in mice treated with carbon tetrachloride (CCl(4...

Descripción completa

Detalles Bibliográficos
Autores principales: González-Fernández, Bárbara, Sánchez, Diana I., Crespo, Irene, San-Miguel, Beatriz, de Urbina, Juan Ortiz, González-Gallego, Javier, Tuñón, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985434/
https://www.ncbi.nlm.nih.gov/pubmed/29892224
http://dx.doi.org/10.3389/fphar.2018.00556