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Loss of Akap1 Exacerbates Pressure Overload-Induced Cardiac Hypertrophy and Heart Failure

Left ventricular hypertrophy (LVH) is a major contributor to the development of heart failure (HF). Alterations in cyclic adenosine monophosphate (cAMP)-dependent signaling pathways participate in cardiomyocyte hypertrophy and mitochondrial dysfunction occurring in LVH and HF. cAMP signals are recei...

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Detalles Bibliográficos
Autores principales: Schiattarella, Gabriele G., Boccella, Nicola, Paolillo, Roberta, Cattaneo, Fabio, Trimarco, Valentina, Franzone, Anna, D’Apice, Stefania, Giugliano, Giuseppe, Rinaldi, Laura, Borzacchiello, Domenica, Gentile, Alessandra, Lombardi, Assunta, Feliciello, Antonio, Esposito, Giovanni, Perrino, Cinzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985454/
https://www.ncbi.nlm.nih.gov/pubmed/29892230
http://dx.doi.org/10.3389/fphys.2018.00558