Cargando…

Prucalopride inhibits the glioma cells proliferation and induces autophagy via AKT-mTOR pathway

BACKGROUNDS: Glioma is the most fatal primary brain glioma in central nervous system mainly attributed to its high invasion. Prucalopride, a Serotonin-4 (5-HT4) receptor agonist, has been reported to regulate neurodevelopment. This study aimed to investigate the influence of the Prucalopride on glio...

Descripción completa

Detalles Bibliográficos
Autores principales: Qiao, Hong, Wang, Yong-Bo, Gao, Yu-Mei, Bi, Li-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985575/
https://www.ncbi.nlm.nih.gov/pubmed/29866060
http://dx.doi.org/10.1186/s12883-018-1083-7