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RNAi-dependent heterochromatin assembly in fission yeast Schizosaccharomyces pombe requires heat-shock molecular chaperones Hsp90 and Mas5

BACKGROUND: Heat-shock molecular chaperone proteins (Hsps) promote the loading of small interfering RNA (siRNA) onto RNA interference (RNAi) effector complexes. While the RNAi process is coupled with heterochromatin assembly in several model organisms, it remains unclear whether the Hsps contribute...

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Detalles Bibliográficos
Autores principales: Okazaki, Kosuke, Kato, Hiroaki, Iida, Tetsushi, Shinmyozu, Kaori, Nakayama, Jun-ichi, Murakami, Yota, Urano, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985592/
https://www.ncbi.nlm.nih.gov/pubmed/29866182
http://dx.doi.org/10.1186/s13072-018-0199-8