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Substance P-modified human serum albumin nanoparticles loaded with paclitaxel for targeted therapy of glioma

The blood–brain barrier (BBB) and the poor ability of many drugs to cross that barrier greatly limits the efficacy of chemotherapies for glioblastoma multiforme (GBM). The present study exploits albumin as drug delivery vehicle to promote the chemotherapeutic efficacy of paclitaxel (PTX) by improvin...

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Detalles Bibliográficos
Autores principales: Ruan, Chunhui, Liu, Lisha, Lu, Yifei, Zhang, Yu, He, Xi, Chen, Xinli, Zhang, Yujie, Chen, Qinjun, Guo, Qin, Sun, Tao, Jiang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985627/
https://www.ncbi.nlm.nih.gov/pubmed/29872625
http://dx.doi.org/10.1016/j.apsb.2017.09.008