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Pokeweed antiviral protein attenuates liver fibrosis in mice through regulating Wnt/Jnk mediated glucose metabolism

BACKGROUND/AIMS: Pokeweed antiviral protein (PAP) has been reported to downregulate Wnt/Jnk pathway and attenuate liver fibrosis. This study was designed to intensively explore the mechanism of anti-fibrosis effect of PAP. MATERIALS AND METHODS: Hepatic stellate cell (HSC) activation was induced by...

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Detalles Bibliográficos
Autores principales: Zhang, Yonghong, Yu, Xiaolan, Wang, Zheng, Yin, Ming, Zhao, Zonghao, Li, Yi, Li, Wenting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985634/
https://www.ncbi.nlm.nih.gov/pubmed/29652027
http://dx.doi.org/10.4103/sjg.SJG_470_17