Improved method for synthesis of low molecular weight protamine–siRNA conjugate

RNAi technology has aroused wide public interest due to its high efficiency and specificity to treat multiple types of diseases. However, the effective delivery of siRNA remains a challenge due to its large molecular weight and strong anionic charge. Considering their remarkable functions in vivo an...

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Detalles Bibliográficos
Autores principales: Yu, Zhili, Ye, Junxiao, Pei, Xing, Sun, Lu, Liu, Ergang, Wang, Jianxin, Huang, Yongzhuo, Lee, Seung Jin, He, Huining
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985694/
https://www.ncbi.nlm.nih.gov/pubmed/29872628
http://dx.doi.org/10.1016/j.apsb.2017.11.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985694/
https://www.ncbi.nlm.nih.gov/pubmed/29872628
http://dx.doi.org/10.1016/j.apsb.2017.11.011

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