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DNA Methylation of PTGIS Enhances Hepatic Stellate Cells Activation and Liver Fibrogenesis

The activation of hepatic stellate cells (HSCs) is a central event in the progression of liver fibrosis. Multiple studies proved that DNA methylation might accelerate HSCs activation. However, the specific pathogenesis of liver fibrosis remains not fully addressed. Our laboratory performed Genome me...

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Detalles Bibliográficos
Autores principales: Pan, Xue-yin, Yang, Yang, Meng, Hong-wu, Li, Hai-di, Chen, Xin, Huang, Hui-min, Bu, Fang-tian, Yu, Hai-xia, Wang, Qin, Huang, Cheng, Meng, Xiao-ming, Li, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985735/
https://www.ncbi.nlm.nih.gov/pubmed/29892223
http://dx.doi.org/10.3389/fphar.2018.00553