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5-(Thiophen-2-yl)-1,3,4-thiadiazole derivatives: synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents

BACKGROUND: Nowadays, cancer is an important public health problem in all countries. Limitations of current chemotherapy for neoplastic diseases such as severe adverse reactions and tumor resistance to the chemotherapeutic drugs have been led to a temptation for focusing on the discovery and develop...

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Detalles Bibliográficos
Autores principales: Gomha, Sobhi M, Edrees, Mastoura M, Muhammad, Zeinab A, El-Reedy, Ahmed AM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985782/
https://www.ncbi.nlm.nih.gov/pubmed/29881258
http://dx.doi.org/10.2147/DDDT.S165276