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The Efficacy of Puromycin and Adriamycin for Induction of Glomerular Failure in Larval Zebrafish Validated by an Assay of Glomerular Permeability Dynamics

Defects in the glomerular filtration barrier (GFB) play a major role in the onset of human renal diseases. Highly ramified glomerular cells named podocytes are a critical component of the GFB. Injury to podocytes results in abnormal excretion of plasma proteins, which can lead to chronic kidney dise...

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Detalles Bibliográficos
Autores principales: Rider, Sebastien Andrew, Bruton, Finnius Austin, Collins, Richard George, Conway, Bryan Ronald, Mullins, John James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985910/
https://www.ncbi.nlm.nih.gov/pubmed/29480793
http://dx.doi.org/10.1089/zeb.2017.1527