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Progression of whole blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in patients with severe influenza

Transcriptional profiles and host response biomarkers are used increasingly to investigate the severity, subtype and pathogenesis of disease. We now describe whole blood mRNA signatures, local and systemic immune mediator concentrations in 131 adults hospitalised with influenza from which extensive...

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Detalles Bibliográficos
Autores principales: Dunning, Jake, Blankley, Simon, Hoang, Long T, Cox, Mike, Graham, Christine M, James, Philip L, Bloom, Chloe I, Chaussabel, Damien, Banchereau, Jacques, Brett, Stephen J., Moffatt, Miriam F, O’Garra, Anne, Openshaw, Peter JM
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985949/
https://www.ncbi.nlm.nih.gov/pubmed/29777224
http://dx.doi.org/10.1038/s41590-018-0111-5