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Progression of whole blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in patients with severe influenza
Transcriptional profiles and host response biomarkers are used increasingly to investigate the severity, subtype and pathogenesis of disease. We now describe whole blood mRNA signatures, local and systemic immune mediator concentrations in 131 adults hospitalised with influenza from which extensive...
Autores principales: | Dunning, Jake, Blankley, Simon, Hoang, Long T, Cox, Mike, Graham, Christine M, James, Philip L, Bloom, Chloe I, Chaussabel, Damien, Banchereau, Jacques, Brett, Stephen J., Moffatt, Miriam F, O’Garra, Anne, Openshaw, Peter JM |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985949/ https://www.ncbi.nlm.nih.gov/pubmed/29777224 http://dx.doi.org/10.1038/s41590-018-0111-5 |
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