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Identifying and exploiting genes that potentiate the evolution of antibiotic resistance

There is an urgent need to develop novel approaches for predicting and preventing the evolution of antibiotic resistance. Here we show that the ability to evolve de novo resistance to a clinically important β-lactam antibiotic, ceftazidime, varies drastically across the genus Pseudomonas. This varia...

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Detalles Bibliográficos
Autores principales: Gifford, Danna, Furió, Victoria, Papkou, Andrei, Vogwill, Tom, Oliver, Antonio, MacLean, R. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5985954/
https://www.ncbi.nlm.nih.gov/pubmed/29686236
http://dx.doi.org/10.1038/s41559-018-0547-x