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Temporospatial induction of homeodomain gene cut dictates natural lineage reprogramming

Understanding how cellular identity naturally interconverts with high efficiency and temporospatial precision is crucial for regenerative medicine. Here, we revealed a natural midgut-to-renal lineage conversion event during Drosophila metamorphosis and identified the evolutionarily-conserved homeodo...

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Detalles Bibliográficos
Autores principales: Xu, Ke, Liu, Xiaodan, Wang, Yuchun, Wong, Chouin, Song, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986271/
https://www.ncbi.nlm.nih.gov/pubmed/29714689
http://dx.doi.org/10.7554/eLife.33934