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Induction of nerve growth factor by phorbol 12-myristate 13-acetate is dependent upon the mitogen activated protein kinase pathway

Several small molecules have been identified that induce glial cells to synthesize and secrete nerve growth factor (NGF), a critical neurotrophin that supports neuronal growth and survival, and as such show promise in the development of drugs for the chemoprevention of Alzheimer's disease. To m...

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Detalles Bibliográficos
Autores principales: Davis, Justin B., Calvert, Valerie, Roberts, Steven, Bracero, Sabrina, Petricoin, Emanuel, Couch, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986306/
https://www.ncbi.nlm.nih.gov/pubmed/29872754
http://dx.doi.org/10.1016/j.heliyon.2018.e00617