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Dietary Neurotransmitters: A Narrative Review on Current Knowledge

Foods are natural sources of substances that may exert crucial effects on the nervous system in humans. Some of these substances are the neurotransmitters (NTs) acetylcholine (ACh), the modified amino acids glutamate and γ-aminobutyric acid (GABA), and the biogenic amines dopamine, serotonin (5-HT),...

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Autores principales: Briguglio, Matteo, Dell’Osso, Bernardo, Panzica, Giancarlo, Malgaroli, Antonio, Banfi, Giuseppe, Zanaboni Dina, Carlotta, Galentino, Roberta, Porta, Mauro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986471/
https://www.ncbi.nlm.nih.gov/pubmed/29748506
http://dx.doi.org/10.3390/nu10050591
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author Briguglio, Matteo
Dell’Osso, Bernardo
Panzica, Giancarlo
Malgaroli, Antonio
Banfi, Giuseppe
Zanaboni Dina, Carlotta
Galentino, Roberta
Porta, Mauro
author_facet Briguglio, Matteo
Dell’Osso, Bernardo
Panzica, Giancarlo
Malgaroli, Antonio
Banfi, Giuseppe
Zanaboni Dina, Carlotta
Galentino, Roberta
Porta, Mauro
author_sort Briguglio, Matteo
collection PubMed
description Foods are natural sources of substances that may exert crucial effects on the nervous system in humans. Some of these substances are the neurotransmitters (NTs) acetylcholine (ACh), the modified amino acids glutamate and γ-aminobutyric acid (GABA), and the biogenic amines dopamine, serotonin (5-HT), and histamine. In neuropsychiatry, progressive integration of dietary approaches in clinical routine made it necessary to discern the more about some of these dietary NTs. Relevant books and literature from PubMed and Scopus databases were searched for data on food sources of Ach, glutamate, GABA, dopamine, 5-HT, and histamine. Different animal foods, fruits, edible plants, roots, and botanicals were reported to contain NTs. These substances can either be naturally present, as part of essential metabolic processes and ecological interactions, or derive from controlled/uncontrolled food technology processes. Ripening time, methods of preservation and cooking, and microbial activity further contributes to NTs. Moreover, gut microbiota are considerable sources of NTs. However, the significance of dietary NTs intake needs to be further investigated as there are no significant data on their bioavailability, neuronal/non neuronal effects, or clinical implications. Evidence-based interventions studies should be encouraged.
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spelling pubmed-59864712018-06-05 Dietary Neurotransmitters: A Narrative Review on Current Knowledge Briguglio, Matteo Dell’Osso, Bernardo Panzica, Giancarlo Malgaroli, Antonio Banfi, Giuseppe Zanaboni Dina, Carlotta Galentino, Roberta Porta, Mauro Nutrients Review Foods are natural sources of substances that may exert crucial effects on the nervous system in humans. Some of these substances are the neurotransmitters (NTs) acetylcholine (ACh), the modified amino acids glutamate and γ-aminobutyric acid (GABA), and the biogenic amines dopamine, serotonin (5-HT), and histamine. In neuropsychiatry, progressive integration of dietary approaches in clinical routine made it necessary to discern the more about some of these dietary NTs. Relevant books and literature from PubMed and Scopus databases were searched for data on food sources of Ach, glutamate, GABA, dopamine, 5-HT, and histamine. Different animal foods, fruits, edible plants, roots, and botanicals were reported to contain NTs. These substances can either be naturally present, as part of essential metabolic processes and ecological interactions, or derive from controlled/uncontrolled food technology processes. Ripening time, methods of preservation and cooking, and microbial activity further contributes to NTs. Moreover, gut microbiota are considerable sources of NTs. However, the significance of dietary NTs intake needs to be further investigated as there are no significant data on their bioavailability, neuronal/non neuronal effects, or clinical implications. Evidence-based interventions studies should be encouraged. MDPI 2018-05-13 /pmc/articles/PMC5986471/ /pubmed/29748506 http://dx.doi.org/10.3390/nu10050591 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Briguglio, Matteo
Dell’Osso, Bernardo
Panzica, Giancarlo
Malgaroli, Antonio
Banfi, Giuseppe
Zanaboni Dina, Carlotta
Galentino, Roberta
Porta, Mauro
Dietary Neurotransmitters: A Narrative Review on Current Knowledge
title Dietary Neurotransmitters: A Narrative Review on Current Knowledge
title_full Dietary Neurotransmitters: A Narrative Review on Current Knowledge
title_fullStr Dietary Neurotransmitters: A Narrative Review on Current Knowledge
title_full_unstemmed Dietary Neurotransmitters: A Narrative Review on Current Knowledge
title_short Dietary Neurotransmitters: A Narrative Review on Current Knowledge
title_sort dietary neurotransmitters: a narrative review on current knowledge
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986471/
https://www.ncbi.nlm.nih.gov/pubmed/29748506
http://dx.doi.org/10.3390/nu10050591
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