Cargando…

Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells

Hypoxia, a hallmark characteristic of glioblastoma (GBM) induces changes in the transcriptome and the proteome of tumor cells. We discovered that hypoxic stress produces significant qualitative and quantitative changes in the protein content of secreted exosomes from GBM cells. Among the proteins fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Kore, Rajshekhar A., Edmondson, Jacob L., Jenkins, Samir V., Jamshidi-Parsian, Azemat, Dings, Ruud P.M., Reyna, Nathan S., Griffin, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986551/
https://www.ncbi.nlm.nih.gov/pubmed/29872742
http://dx.doi.org/10.1016/j.bbrep.2018.03.008