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Hypoxia-derived exosomes induce putative altered pathways in biosynthesis and ion regulatory channels in glioblastoma cells
Hypoxia, a hallmark characteristic of glioblastoma (GBM) induces changes in the transcriptome and the proteome of tumor cells. We discovered that hypoxic stress produces significant qualitative and quantitative changes in the protein content of secreted exosomes from GBM cells. Among the proteins fo...
Autores principales: | Kore, Rajshekhar A., Edmondson, Jacob L., Jenkins, Samir V., Jamshidi-Parsian, Azemat, Dings, Ruud P.M., Reyna, Nathan S., Griffin, Robert J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986551/ https://www.ncbi.nlm.nih.gov/pubmed/29872742 http://dx.doi.org/10.1016/j.bbrep.2018.03.008 |
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