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Bcl-2 inhibition sensitizes triple-negative human breast cancer cells to doxorubicin

Breast cancers can be divided into several types. Because triple-negative breast cancer (TNBC) is the most refractory to current anti-cancer therapies, efficient treatment has been urgently required. Members of the Bcl-2 family play pro- and anti-apoptotic roles in mitochondria-mediated apoptosis. S...

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Detalles Bibliográficos
Autores principales: Inao, Touko, Iida, Yuichi, Moritani, Tamami, Okimoto, Tamio, Tanino, Ryosuke, Kotani, Hitoshi, Harada, Mamoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986635/
https://www.ncbi.nlm.nih.gov/pubmed/29876007
http://dx.doi.org/10.18632/oncotarget.25370