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Anticancer drugs-related QTc prolongation, torsade de pointes and sudden death: current evidence and future research perspectives

Anticancer drugs may have proarrhythmic effects including drug-induced QT interval prolongation, which is of particular importance because it can lead to a fatal polymorphic ventricular tachycardia termed torsade de pointes (TdP). QT interval prolongation and TdP are rare life-threatening untoward e...

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Detalles Bibliográficos
Autores principales: Duan, Jialin, Tao, Jingwen, Zhai, Maocai, Li, Chengpeng, Zhou, Ning, Lv, Jiagao, Wang, Lin, Lin, Li, Bai, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986642/
https://www.ncbi.nlm.nih.gov/pubmed/29876021
http://dx.doi.org/10.18632/oncotarget.25008