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Engineering of a rough auxotrophic mutant Salmonella Typhimurium for effective delivery
Live Salmonella vaccine vectors offer a remarkable platform for delivering immunogens and therapeutic molecules by mimicking natural intracellular infections; however, pre-existing anti-vector immunity can impede effective deployment. Measures to alleviate pre-existing immunity include the use of he...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986645/ https://www.ncbi.nlm.nih.gov/pubmed/29876000 http://dx.doi.org/10.18632/oncotarget.25192 |