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Concurrent, but not sequential, PD-1 blockade with a DNA vaccine elicits anti-tumor responses in patients with metastatic, castration-resistant prostate cancer

T-cell checkpoint inhibitors have demonstrated dramatic clinical activity against multiple cancer types, however little activity in patients with prostate cancer. Conversely, an anti-tumor vaccine was approved for the treatment of prostate cancer, having demonstrated an improvement in overall surviv...

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Detalles Bibliográficos
Autores principales: McNeel, Douglas G., Eickhoff, Jens C., Wargowski, Ellen, Zahm, Christopher, Staab, Mary Jane, Straus, Jane, Liu, Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986652/
https://www.ncbi.nlm.nih.gov/pubmed/29876010
http://dx.doi.org/10.18632/oncotarget.25387