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A quantitative characterization of interaction between prion protein with nucleic acids

Binding of recombinant prion protein with small highly structured RNAs, prokaryotic and eukaryotic prion protein mRNA pseudoknots, tRNA and polyA has been studied by the change in fluorescence anisotropy of the intrinsic tryptophan groups of the protein. The affinities of these RNAs to the prion pro...

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Detalles Bibliográficos
Autores principales: Bera, Alakesh, Biring, Sajal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986701/
https://www.ncbi.nlm.nih.gov/pubmed/29872743
http://dx.doi.org/10.1016/j.bbrep.2018.04.006