Sorting nexin 10 controls mTOR activation through regulating amino-acid metabolism in colorectal cancer

Amino-acid metabolism plays a vital role in mammalian target of rapamycin (mTOR) signaling, which is the pivot in colorectal cancer (CRC). Upregulated chaperone-mediated autophagy (CMA) activity contributes to the regulation of metabolism in cancer cells. Previously, we found that sorting nexin 10 (...

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Detalles Bibliográficos
Autores principales: Le, Yunchen, Zhang, Sulin, Ni, Jiahui, You, Yan, Luo, Kejing, Yu, Yunqiu, Shen, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986761/
https://www.ncbi.nlm.nih.gov/pubmed/29867114
http://dx.doi.org/10.1038/s41419-018-0719-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986761/
https://www.ncbi.nlm.nih.gov/pubmed/29867114
http://dx.doi.org/10.1038/s41419-018-0719-2

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