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RAGE-dependent mitochondria pathway: a novel target of silibinin against apoptosis of osteoblastic cells induced by advanced glycation end products

Advanced glycation end products (AGEs) can stimulate osteoblast apoptosis and have a critical role in the pathophysiology of diabetic osteoporosis. Mitochondrial abnormalities are closely related to osteoblast dysfunction. However, it remains unclear whether mitochondrial abnormalities are involved...

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Detalles Bibliográficos
Autores principales: Mao, Y. X., Cai, W. J., Sun, X. Y., Dai, P. P., Li, X. M., Wang, Q., Huang, X. L., He, B., Wang, P. P., Wu, G., Ma, J. F., Huang, S. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986782/
https://www.ncbi.nlm.nih.gov/pubmed/29867140
http://dx.doi.org/10.1038/s41419-018-0718-3