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RAGE-dependent mitochondria pathway: a novel target of silibinin against apoptosis of osteoblastic cells induced by advanced glycation end products
Advanced glycation end products (AGEs) can stimulate osteoblast apoptosis and have a critical role in the pathophysiology of diabetic osteoporosis. Mitochondrial abnormalities are closely related to osteoblast dysfunction. However, it remains unclear whether mitochondrial abnormalities are involved...
Autores principales: | Mao, Y. X., Cai, W. J., Sun, X. Y., Dai, P. P., Li, X. M., Wang, Q., Huang, X. L., He, B., Wang, P. P., Wu, G., Ma, J. F., Huang, S. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986782/ https://www.ncbi.nlm.nih.gov/pubmed/29867140 http://dx.doi.org/10.1038/s41419-018-0718-3 |
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