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Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity

Development of a multiple-chambered heart from the linear heart tube is inherently linked to cardiac looping. Although many molecular factors regulating the process of cardiac chamber ballooning have been identified, the cellular mechanisms underlying the chamber formation remain unclear. Here, we d...

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Detalles Bibliográficos
Autores principales: Merks, Anne Margarete, Swinarski, Marie, Meyer, Alexander Matthias, Müller, Nicola Victoria, Özcan, Ismail, Donat, Stefan, Burger, Alexa, Gilbert, Stephen, Mosimann, Christian, Abdelilah-Seyfried, Salim, Panáková, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986786/
https://www.ncbi.nlm.nih.gov/pubmed/29867082
http://dx.doi.org/10.1038/s41467-018-04566-1