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Planar cell polarity signalling coordinates heart tube remodelling through tissue-scale polarisation of actomyosin activity
Development of a multiple-chambered heart from the linear heart tube is inherently linked to cardiac looping. Although many molecular factors regulating the process of cardiac chamber ballooning have been identified, the cellular mechanisms underlying the chamber formation remain unclear. Here, we d...
Autores principales: | Merks, Anne Margarete, Swinarski, Marie, Meyer, Alexander Matthias, Müller, Nicola Victoria, Özcan, Ismail, Donat, Stefan, Burger, Alexa, Gilbert, Stephen, Mosimann, Christian, Abdelilah-Seyfried, Salim, Panáková, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986786/ https://www.ncbi.nlm.nih.gov/pubmed/29867082 http://dx.doi.org/10.1038/s41467-018-04566-1 |
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